Which PPE item must meet FFP3 standard when handling cytotoxic medications?

• A. Gown - long sleeved and water resistant.
• B. Gloves - cytotoxic resistant.
• C. Splash guard and maybe goggles.
• D. Respiratory protective equipment - must be FFP3 standard.

Answer: (D)

Handling cytotoxic medications can generate aerosols, so protecting the inhalation route is essential. Respiratory protective equipment that meets the FFP3 standard provides the highest level of filtration available in typical PPE, blocking at least 99% of airborne particles. This is crucial because inhaling aerosols containing cytotoxic agents poses a serious exposure risk. Other PPE like a gown protects skin and clothing, gloves protect hands, and splash guards or goggles guard against splashes to the eyes, but none of these prevent inhalation of aerosols. Therefore, the PPE item that must meet FFP3 is the respiratory protective equipment, used with proper fit and technique in combination with the other protections.